Demadex

CAS: 56211-40-6
Molecular Formula: C16H20N4O3S
Molecular Weight: 348.42
Product description:White crystalline powder, melting point 163-164 ℃, soluble in water.There is the Na + and diuresis, C1 - role, but not significant change in glomerular filtration rate, renal plasma flow and acid-base balance. Applied to pulp loops rise a thick section, interfere with the luminal membrane Na +, K +, 2 c1 - symporter system, inhibition of cl - and Na + absorption, higher concentration of NaCl, the lumen liquid osmotic pressure increase, renal medulla between liquid NaCl to reduce, reduce the osmotic pressure gradient, which interfere with the urine concentration process, make the urine Na +, cl - and water discharge increases.