Ciprostene Calcium

Product Name : Ciprostene Calcium
Synonyms : U-61431F Ciprostene calcium
CAS No : 81703-55-1
Molecular  Fomula :  C44H72Ca2O8
Molecular Weight : 769.1
Product Description :
This compound is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. It exhibits biological activity similar to PGI2, yet is 30-fold less potent. Ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 ?g/kg/min in patas monkeys. Also, ciprostene inhibits ADP-induced platelet aggregation ex vivo and in vitro with ID50 values of 9.1 ?g/kg/min and 60 ng/ml, respectively.