Clioquinol

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Clioquinol

CAS: 130-26-7
Molecular Formula: C9H5ClINO
Molecular weight:305.50
Appearance:yellow powder
Density: 2.047 g/cm3
Melting point:175-183°C
Boiling point:350.424°C
Flash point:165°C
Product description :Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities. Clioquinol forms a stable chelate with copper (copper (II) ions), which inhibits the chymotrypsin-like activity of the proteasome; consequently, ubiquitinated proteins may accumulate in tumor cells, followed by tumor cell apoptosis and the inhibition of tumor angiogenesis. It is used to treat infections of the skin and to help provide relief from the redness, itching, and discomfort of many skin problems.

 

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