Tetrapeptide‑27

Product Description

Tetrapeptide‑27 is a synthetic peptide (sequence: P‑E‑K‑K: Proline‑Glutamic acid‑Lysine‑Lysine) known for its skin-brightening and anti-inflammatory effects. It works by reducing the expression of UV-induced POMC/α‑MSH in keratinocytes, effectively inhibiting melanin synthesis to reduce hyperpigmentation and dark spots. Additionally, it calms inflammation and may help soothe acne-prone skin. This multi-functional peptide is ideal for brightening and calming skincare formulations aiming for an even, blemish-free complexion without irritation.

Product Specification

• INCI Name: Tetrapeptide‑27
• Appearance: White to off-white powder
• Solubility: Water-soluble (synthetic peptide)
• Stability: Stable under normal cosmetic storage conditions
• Properties: Brightening, anti‑pigmentation, anti-inflammatory, skin-soothing

Key Benefits & Mechanism

Brightening: Suppresses UV-induced POMC/α‑MSH expression, reducing melanin synthesis and dark spots

Recommended Applications

- Brightening serums and creams targeting dark spots
- Anti-inflammatory or acne-calming skincare
- Daily use products for sensitive or uneven skin tone