What is Oligopeptide-10 in skincare?

What is Oligopeptide-10?
Oligopeptide-10 is a short-chain peptide that’s been gaining popularity in the skincare world, especially among those with sensitive or acne-prone skin. Peptides are small proteins made up of amino acids, and this particular one is known for its antimicrobial and soothing properties.
How Does It Work?
Oligopeptide-10 works by targeting the bacteria that often cause breakouts—specifically Propionibacterium acnes (now called Cutibacterium acnes). It helps reduce inflammation and prevents bacteria from multiplying, making it a gentle yet effective alternative to harsher acne treatments like benzoyl peroxide.
Benefits for Your Skin
What are the benefits of Oligopeptide-10? One of the main perks of Oligopeptide-10 is that it helps calm the skin while fighting blemishes. It’s great for reducing redness, soothing irritation, and supporting the skin barrier. Plus, it plays nicely with other ingredients, often being paired with salicylic acid or niacinamide for enhanced results without the dryness or flaking.
Who Should Use It?
If you’re dealing with acne, oily skin, or even just occasional breakouts, Oligopeptide-10 can be a gentle but effective addition to your routine. It’s especially helpful for people with sensitive skin who struggle with more aggressive acne treatments.
How to Incorporate It
You’ll often find Oligopeptide-10 in serums, spot treatments, and lightweight moisturizers. It’s usually applied after cleansing and before moisturizing. Because it’s non-irritating, you can use it daily—even twice a day, depending on your skin’s needs.
The Bottom Line
Oligopeptide-10 might not be the most famous skincare ingredient (yet), but it’s definitely one to watch. Its unique ability to fight acne-causing bacteria while keeping the skin calm and balanced makes it a valuable player in any skincare routine.