Tesamorelin vs Ipamorelin

If you’re exploring growth hormone - releasing peptides (GHRPs) for health goals like fat loss or muscle growth, Tesamorelin and Ipamorelin are top options—but they differ keyly. This short guide breaks down their core traits for Google users seeking clarity.

Tesamorelin is a synthetic peptide that targets the somatostatin system to boost growth hormone (GH). Its main strength is reducing abdominal fat, proven in studies (e.g., for HIV - associated lipodystrophy). It has minimal impact on muscle mass and may aid cognition/bone density.

Ipamorelin binds to ghrelin receptors to stimulate GH, with high specificity—it doesn’t spike cortisol or prolactin. It excels at muscle support, workout recovery, and better sleep. It may slightly boost metabolism for fat loss, but this is weaker than Tesamorelin’s effect.

For choice: Pick Tesamorelin if your priority is abdominal fat reduction. Choose Ipamorelin for muscle goals or anti - aging with fewer side effects. Both use subcutaneous injections (daily or 5 - on - 2 - off) and have mild side effects (injection site redness, nausea).

Safety note: Avoid if you have active cancer, severe organ disease, or pituitary issues (pregnant/breastfeeding too). Always use under medical supervision for proper dosing (0.2–1mg/day).