Tenofovir Disoproxil

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Product Name: Tenofovir Disoproxil

Other Names: Tenofovir Disoproxil Fumarate (TDF), Viread, Bis(POC)PMPA

CAS No.: 201341-05-1

Molecular Formula: C₁₉H₃₀N₅O₁₀P (as fumarate)

Specification: Purity ≥ 98.8%, available as a white to off-white crystalline powder or tablets, complies with USP standards

Appearance and Color: White to off-white crystalline powder

Ingredient Information: Tenofovir Disoproxil, usually sold as its fumarate salt, is a drug made by tweaking tenofovir to make it easier for the body to absorb when taken by mouth. It’s got carbon, hydrogen, nitrogen, oxygen, and phosphorus, and turns into tenofovir inside the body. It’s not very water-soluble (about 13.4 mg/mL), and it’s made into a stable powder or tablets. Tons of it—over 10,000 tons a year—are produced worldwide to help treat HIV and hepatitis B.

Uses: This stuff is a key player in fighting HIV-1 and hepatitis B. It’s used in meds like Viread or generics to keep the virus in check, taken at 300 mg a day, and works great for both adults and kids (over 2 years old, at least 10 kg). It’s also part of combo drugs like Truvada, which can prevent HIV (called PrEP) with up to 90-100% success if taken right. Plus, it’s used in studies to figure out how antiviral drugs work or why resistance happens, though doctors keep an eye out for side effects like kidney issues or bone loss.