TAT-GluA2 3Y

TAT-GluA2 3Y

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Product Name: TAT-GluA2 3Y
CAS No.: 1404188-93-7
Molecular Formula: C115H185N43O29
Molecular Weight: 2634 g/mol
Appearance: White to off-white powder

Product Introduction:
TAT-GluA2 3Y is a synthetic peptide designed to inhibit AMPA receptor endocytosis. It is widely used in neuroscience research to study synaptic plasticity, learning, and memory mechanisms by blocking receptor internalization and stabilizing surface GluA2-containing AMPA receptors.

Function:
TAT-GluA2 3Y prevents the internalization of AMPA receptors, thereby maintaining synaptic strength and stability. It has been shown to block long-term depression (LTD) at glutamatergic synapses and exhibits neuroprotective and antinociceptive properties. Researchers often use it to explore mechanisms underlying synaptic regulation, neuropathic pain, and cognitive function.

 

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