Sorafenib Tosylate

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Product Name: Sorafenib Tosylate

Other Names: Sorafenib p-toluenesulfonate, Nexavar

CAS No.: 284461-73-0

Molecular Formula: C₂₁H₁₆ClF₃N₄O₃

Specification: Sorafenib Tosylate is typically available as a white to off-white or slightly yellowish crystalline powder, supplied in high-purity forms (98% or greater) for pharmaceutical use, often formulated as 200 mg film-coated tablets for oral administration.

Appearance and Color: white to off-white powder

Ingredient Information: Sorafenib Tosylate is the tosylate salt of sorafenib, a multi-kinase inhibitor, synthetically produced, commonly formulated with excipients like microcrystalline cellulose, croscarmellose sodium, and magnesium stearate in commercial tablets.

Uses: Sorafenib Tosylate is widely used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and differentiated thyroid carcinoma by inhibiting tumor angiogenesis and proliferation; it is also studied for its potential in other cancers due to its action on RAF, VEGF, and PDGF receptors.