Rapamycin

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Product Information:
Product Name: Rapamycin (Sirolimus)
CAS No.: 53123-88-9
Molecular Formula: C₅₁H₇₉NO₁₃
Molecular Weight: 914.18 g/mol
Appearance: White to off-white powder

Product Introduction:
Rapamycin, also known as Sirolimus, is a natural macrolide antibiotic produced by the bacterium *Streptomyces hygroscopicus*. It is primarily recognized for its immunosuppressive properties and is commonly used to prevent organ transplant rejection. Additionally, Rapamycin serves as a potent inhibitor of the mammalian target of rapamycin (mTOR), a central regulator of cell growth and metabolism.

Function:
Rapamycin exerts its effects by binding to the immunophilin FKBP-12, forming a complex that inhibits mTORC1. This inhibition leads to reduced protein synthesis and cell proliferation, making Rapamycin valuable in preventing transplant rejection and treating certain cancers. Its ability to modulate the immune system also makes it useful in various autoimmune disorders.