Kanamycin Monosulfate

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Product Name: Kanamycin Monosulfate

Other Names: Kanamycin A, Kanamycin Sulfate, Ophtalmokalixan

CAS No.: 25389-94-0

Molecular Formula: C₁₈H₃₈N₄O₁₅S

Specification: Purity ≥ 98%, available as a white to off-white crystalline powder, complies with USP standards

Appearance and Color: White to off-white crystalline powder

Ingredient Information: Kanamycin Monosulfate, also called Kanamycin A, is an antibiotic from the bacterium Streptomyces kanamyceticus, made by fermenting the bacteria and purifying the product as a sulfate salt. It’s got carbon, hydrogen, nitrogen, oxygen, and sulfur, and works by sticking to bacterial ribosomes to stop protein production. It’s water-soluble (up to 1000 mg/mL at 20°C), stable as a powder, and comes as a fine, odorless powder used in labs and medicine.

Uses: This stuff is a go-to in labs for keeping cell cultures free of bacteria, used at about 30-100 mg/L to kill off gram-negative and some gram-positive bacteria. It’s also key in molecular biology as a selective agent, helping pick out cells with kanamycin resistance genes (like NptII) in genetic engineering, with millions of grams used yearly in biotech. In medicine, it treats serious infections like pneumonia or tuberculosis, given as injections (7-10 days max), but it’s not first-line due to side effects like hearing loss or kidney issues. It’s also used in research to study bacterial resistance, though it’s tightly controlled due to risks in pregnancy.