Gonadorelin acetate

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[ Introduction ]
Gonadorelin acetate is a synthetic decapeptide analogue of endogenous gonadotropin-releasing hormone (GnRH), acting as a GnRH agonist. It stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary.

[ Uses ]
It is utilized in fertility medicine to induce gonadotropin secretion and assist in diagnosing pituitary function. Clinical applications include treating primary hypothalamic amenorrhea, hypogonadotropic hypogonadism, delayed puberty, cryptorchidism, and infertility.

[ Specifications ]
Appearance: White powder
CAS Number: 34973-08-5
Molecular Formula: C₅₇H₇₉N₁₇O₁₅
pH Value: Typically formulated in buffered solutions; specific pH not commonly specified
Solubility: Soluble in organic solvents—approximately 0.25 mg/mL in ethanol, ~30 mg/mL in DMSO/DMF; roughly 10 mg/mL in aqueous buffer at pH 7.2
Ingredient: Gonadorelin acetate (active peptide); may include acetate and water in salt/hydrate forms
Storage: Highly moisture-sensitive; store at 2–8 °C or at –20 °C for longer-term stability. Use well-sealed, desiccated containers