Gonadorelin

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[ Description ]
Gonadorelin is a synthetic decapeptide identical to the natural gonadotropin-releasing hormone (GnRH). It is commonly used in medicine to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland.

[ Source and Characteristics ]
[ source: ] Produced by solid-phase peptide synthesis; synthetic GnRH decapeptide.
[ appearance: ] White to off-white sterile powder for reconstitution, also available in injection or nasal spray formulations.
[ CAS: ] 33515-09-2
[ Molecular Formula: ] C₅₅H₇₅N₁₇O₁₃

[ Main Components ]
- Decapeptide sequence: pyroglutamyl-histidyl-tryptophyl-seryl-tyrosyl-glycyl-leucyl-arginyl-prolyl-glycinamide.
- May be present as diacetate or hydrochloride salt depending on formulation.

[ Applications ]
1. Used as a diagnostic agent to evaluate hypothalamic-pituitary function.
2. Treatment of hypogonadotropic hypogonadism.
3. Induction of ovulation in women with hypothalamic amenorrhea or irregular ovulation.
4. Management of delayed puberty.
5. Treatment of cryptorchidism (undescended testicles).
6. Veterinary applications, such as treatment of infertility and estrus control in animals.