Ficusin

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Introduction

Ficusin is a prenylated flavonoid isolated from Ficus species and related plants such as Ficus hispida and Psoralea corylifolia. It appears as a yellow crystalline powder and is widely used in natural product research.

Uses

• Applied in antioxidant, anti-inflammatory, and cytotoxicity screening in cell-based assays.
• Used in metabolic studies for potential antidiabetic and lipid-lowering effects through GLUT4 and PPARγ pathways.
• Serves as a phytochemical reference standard in chromatographic and spectroscopic identification.
• Ensure correct CAS number and structure verification before use for specific research purposes.

Specifications

Source: Primarily isolated and extracted from plants such as Psoralea corylifolia

Chemical formula: C₁₁H₆O₃

Molecular weight:186.16 g/mol

CAS number: 66-97-7

Appearance: Yellow to off-white crystalline powder

Purity: ≥98% (HPLC, research grade)

Solubility: Insoluble in water, but easily soluble in organic solvents such as ethanol, chloroform, and ether

Main Uses and Effects

Treatment of psoriasis: Ficusin can inhibit excessive proliferation of skin cells, reverse multidrug resistance, and reduce inflammation and cell migration by inhibiting NF-κB activation.
Other biological activities: It possesses anticancer, anti-inflammatory, and photosensitizing effects, but high doses or improper use may cause phototoxicity (such as skin burns) or hepatotoxicity.

Storage & Handling

Store in a tightly sealed container at 2–8 °C for short-term use or at −20 °C for long-term storage.
Protect from light, heat, and moisture. Refer to supplier COA/MSDS for detailed stability and safety data.