Epalrestat
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[ Description ]
Epalrestat is an oral medication used to treat diabetic peripheral neuropathy. It works by inhibiting aldose reductase, reducing the accumulation of sorbitol in nerve cells, which helps relieve numbness, tingling, and other discomfort in the hands and feet, thereby improving nerve function. It is one of the commonly used neuroprotective drugs in several Asian countries.
[ Source and Characteristics ]
[ source: ] A synthetic pharmaceutical compound designed to inhibit the enzyme aldose reductase.
[ appearance: ] White powder.
[ CAS: ] 82159-09-9
[ Molecular Formula: ] C₁₅H₁₃NO₃S₂
[ Applications ]
1. Treatment of diabetic peripheral neuropathy.
2. Reduction of intracellular sorbitol accumulation in nerve tissues by inhibiting aldose reductase.
3. Improvement of nerve conduction velocity and other neurological function indicators in diabetic patients.
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