Dofetilide

High-purity Dofetilide. Contact us today to get the best price and secure your order quickly.

Product Overview

Dofetilide is a class III antiarrhythmic drug that selectively blocks the rapid component of the delayed rectifier potassium current (I_Kr) by inhibiting the hERG potassium channel. It is primarily used to convert and maintain normal sinus rhythm in patients with atrial fibrillation or atrial flutter. By prolonging the cardiac action potential and refractory period, it helps stabilize heart rhythm effectively.

Product Benefits

• Restores and maintains normal sinus rhythm in patients with atrial fibrillation or atrial flutter.
• Provides selective potassium channel blockade with minimal effects on sodium or calcium channels.
• Demonstrates high specificity in prolonging repolarization without significant negative inotropic effects.

Product Specifications

• Appearance and Color: White to off-white crystalline powder
• CAS Number: 115256-11-6
• Molecular Formula: C₁₉H₂₇N₃O₅S₂
• Molecular Weight: 441.56 g/mol
• Storage: Store in a tightly sealed container in a cool, dry place, protected from light and moisture. Recommended storage temperature is 2–8 °C or at room temperature depending on formulation.