Darunavir Ethanolate

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[ Description ]

Darunavir ethanolate is the ethanolate salt form of darunavir, a potent HIV-1 protease inhibitor that prevents viral maturation by blocking the cleavage of viral polyproteins. It is widely used in combination antiretroviral therapy to manage HIV infection.

[ Source and Characteristics ]

[ source: ] Synthetic pharmaceutical active ingredient belonging to the protease inhibitor class
[ appearance: ] White to off-white crystalline powder
[ CAS: ] 635728-49-3
[ Molecular Formula: ] C₂₉H₄₃N₃O₈S

[ Applications ]

1. Treatment of HIV-1 infection as part of combination antiretroviral therapy.
2. Effective in patients infected with HIV strains resistant to earlier protease inhibitors.
3. Used with pharmacokinetic enhancers such as ritonavir or cobicistat to maintain therapeutic plasma levels and achieve sustained viral suppression.