Colistin Sulfate

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Product Name: Colistin Sulfate
CAS No.: 1264-72-8
Molecular Formula: C53H102N16O17S
Molecular Weight: 1267.5 g/mol
Purity: ≥98%
Appearance: White to off-white powder

Uses: Colistin Sulfate is used as a potent polymyxin antibiotic against Gram-negative bacteria, applied in microbiological tests, selective media, and research of antimicrobial resistance.

Product Introduction: Colistin Sulfate is the sulfate salt form of the antibiotic colistin (polymyxin E). It comprises multiple structurally related polypeptides, primarily polymyxin E1 and E2, and acts by disrupting the outer membrane of Gram-negative bacterial cells via displacement of divalent cations from lipopolysaccharide layers. It is widely used in research and analytical settings, including susceptibility testing, studying resistance mechanisms, and selective cultivation of Gram-negative organisms. Proper handling is required due to known nephro- and neuro-toxicity, and attention to potential development of resistance is critical.