Bivalirudin

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Product Name: Bivalirudin

Other Names: Angiomax; Angiox; BG‑8967; Hirulog‑1

Product Introduction: Bivalirudin is a synthetic 20‑amino‑acid peptide anticoagulant that directly and reversibly inhibits thrombin by binding both the catalytic site and the anion‑binding exosite. It offers rapid onset, predictable anticoagulant effect, and reduced bleeding risk. Widely used in percutaneous coronary intervention and in patients with or at risk of heparin‑induced thrombocytopenia.

CAS Number: 128270‑60‑0

Molecular Formula: C₉₈H₁₃₈N₂₄O₃₃

Specification: ≥98 % purity powder (trifluoroacetate salt), typically crystalline solid; sequence D‑Phe‑Pro‑Arg‑Pro‑Gly‑Gly‑Gly‑Gly‑Asn‑Gly‑Asp‑Phe‑Glu‑Glu‑Ile‑Pro‑Glu‑Glu‑Tyr‑Leu; water soluble (~10 mg/mL), DMSO ~30 mg/mL

Appearance: White to off‑white solid powder

Ingredient: Synthetic bivalirudin peptide (20 amino acids matching human sequence)

Functions: Acts as a direct thrombin inhibitor; blocks both circulating and clot‑bound thrombin, prevents fibrin formation and platelet activation; commonly applied during PCI procedures and for anticoagulation in HIT/HITTS patients, offering rapid onset, short half‑life, and reversible action.