Atosiban

Looking for high‑purity Atosiban for research applications in preterm labor models, oxytocin/vasopressin receptor studies, or peptide pharmacology? We offer Atosiban with consistent activity, ≥ 98% purity, and reliable supply. Contact us for pricing and technical documentation.

Product Name: Atosiban

Other Names: Tractocile, Antocin, RWJ‑22164, RW22164 (deamino‑oxytocin analogue)

Product Introduction: Atosiban is a cyclic nonapeptide and a competitive antagonist of oxytocin and vasopressin V₁ₐ receptors. It inhibits uterine contractions by preventing oxytocin‑mediated intracellular calcium signaling and prostaglandin release. Noted for its rapid onset (within ~10 minutes) and favorable safety profile compared to β‑agonists, it is widely used in tocolysis research and receptor‑binding studies.

CAS Number: 90779‑69‑4

Molecular Formula: C₄₃H₆₇N₁₁O₁₂S₂

Specification: ≥98% purity by HPLC (typical research grade)

Appearance: White to off‑white crystalline powder

Ingredient: Synthetic cyclic nonapeptide corresponding to desamino‑oxytocin analogue

Functions:
1. Antagonizes oxytocin receptors to suppress uterine contractions
2. Blocks vasopressin V₁ₐ (and to some extent V₁b/V₂) receptors in research 3. Used in preterm labor and tocolytic mechanism studies and pharmacodynamics research
4. Enables assay development for receptor binding and intracellular Ca²⁺ signaling pathways
5. Suitable for pharmacology, peptide engineering, and drug development research