ARA-290

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[ Introduction ]
ARA-290, also known as Cibinetide, is a synthetic 11-amino-acid peptide derived from the helix-B surface of erythropoietin (EPO). It selectively activates the innate repair receptor, promoting anti-inflammatory and tissue-protective effects without stimulating red blood cell production.

[ Uses ]
ARA-290 is investigated for its therapeutic potential in neuropathic pain, small fiber neuropathy, diabetes-related complications, and inflammatory conditions. It has shown benefits in improving metabolic parameters, nerve function, and tissue repair in both preclinical and clinical studies.

[ Specifications ]
Appearance: White to off-white powder
CAS Number: 1208243-50-8
Molecular Formula: C₅₁H₈₄N₁₆O₂₁
Molecular Weight: ~1257 g/mol
pH Value: Neutral in aqueous buffer solutions
Solubility: Water-soluble; compatible with standard laboratory buffers
Ingredient: Synthetic 11-amino-acid peptide (sequence mimicking helix B of EPO)
Storage: Store at −20 °C or below; avoid repeated freeze–thaw cycles