Amlexanox

Amlexanox

Looking for bulk Amlexanox powder for topical ulcer treatments? High-purity Amlexanox supplier with guaranteed ≥98% HPLC purity. Reliable Amlexanox manufacturer for pharmaceutical and research use.

Product Name: Amlexanox

Product Introduction:
Amlexanox (IUPAC: 2-amino-7‑isopropyl‑5-oxo‑5H‑chromeno[2,3‑b]pyridine‑3‑carboxylic acid) is an antiallergic and anti‑inflammatory agent, commonly used in a 5% topical paste (Aphthasol®) to treat recurrent aphthous ulcers, reducing healing time and pain. It inhibits the release of histamine and leukotrienes, and selectively blocks IKKε and TBK1 kinases—showing promise in inflammatory conditions and metabolic disorders. It is a white to off‑white crystalline powder, soluble in water and DMSO, suitable for research and pharmaceutical formulations.

 

CAS No.: 68302‑57‑8

Molecular Formula: C16H14N2O4

Molecular Weight: 298.298 g/mol

Appearance: White to off‑white crystalline powder

Uses:
Amlexanox is primarily formulated as a 5% topical paste to treat canker sores by reducing ulcer duration and discomfort. It has also been used in Japan to treat allergic rhinitis, asthma, and conjunctivitis. Additionally, its mechanism as an IKKε/TBK1 inhibitor has led to research into applications for weight management, insulin sensitivity, and inflammatory diseases.

 

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