Adipotide

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[ Description ]
Adipotide (also known as Prohibitin-targeting peptide 1 or TP01) is a synthetic peptidomimetic developed as a targeted proapoptotic agent. It is designed to selectively disrupt the blood vessels supplying white adipose tissue, leading to apoptosis of fat cells in experimental models.

[ Source and Characteristics ]
[ source: ] Laboratory-synthesized peptide for research purposes
[ appearance: ] White to off-white lyophilized powder
[ CAS: ] 859216-15-2
[ Molecular Formula: ] C₁₁₁H₂₀₄N₃₆O₂₈S₂

[ Main Components ]
Adipotide consists of the peptide sequence CKGGRAKDC-GG-D(KLAKLAK)₂, specifically designed to bind prohibitin and ANXA2 proteins on the vasculature of white adipose tissue.

[ Applications ]
1. Induction of apoptosis in blood vessels supplying white adipose tissue.
2. Experimental anti-obesity agent in preclinical studies.
3. Improvement of insulin sensitivity and glucose regulation in obese models.
4. Research into selective vascular targeting strategies.
5. Investigational use in metabolic disease studies and fat reduction research.