Actinomycin D

Advance cancer and molecular biology research with high-purity Actinomycin D.

Buy research-grade Actinomycin D for biochemical and pharmaceutical studies from Bolise Co., Ltd.

Introduction

Actinomycin D, also known as Dactinomycin, is an antibiotic and antineoplastic compound isolated from Streptomyces species. It functions by intercalating into DNA and inhibiting RNA synthesis, making it a valuable tool in molecular biology research and a clinically important chemotherapeutic agent. Actinomycin D is widely used in studies involving gene expression, transcription regulation, and cancer cell proliferation.

Uses

• Antitumor research: Used to study mechanisms of tumor inhibition and apoptosis induction in cancer cells.
• Gene expression studies: Serves as a transcription inhibitor to analyze RNA synthesis pathways.
• Pharmaceutical development: Used in preclinical research for developing anticancer drugs and therapeutic strategies.

Specifications

• Appearance: Orange to red crystalline powder
• CAS: 50-76-0
• Molecular Formula: C₆₂H₈₆N₁₂O₁₆
• Composition: ≥ 98% Actinomycin D (HPLC)
• Storage: Store at 2–8°C in a tightly sealed container; protect from light and moisture.

Precautions

For laboratory research use only. Actinomycin D is a cytotoxic compound; handle with extreme care under a fume hood using proper protective equipment. Avoid inhalation, ingestion, or skin contact. Dispose of waste according to institutional and environmental safety regulations. Not for human or animal therapeutic use.