Sh-Pentapeptide-5

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Product Description

Sh-Pentapeptide-5 is a synthetic recombinant pentapeptide with the same amino acid sequence as Leu-enkephalin (Tyr-Gly-Gly-Phe-Leu). It exhibits a Botox-like mechanism by relaxing facial muscle contractions and mimicking the effects of epidermal growth factor (EGF) to promote skin regeneration and repair. This peptide helps reduce expression lines and deep wrinkles, improve skin smoothness and firmness, and enhance overall elasticity and radiance. Often formulated together with potassium glutathionate isomerized linoleate in the Peptilift complex, it provides improved skin penetration, hydration, antioxidant protection, and detoxifying benefits. It is widely used in anti-aging, lifting, and skin-repair cosmetic formulations.

Product Specification

• INCI Name: Sh-Pentapeptide-5
• Chemical Name: Leu-enkephalin (Tyr-Gly-Gly-Phe-Leu)
• CAS Number: 58822-25-6
• Molecular Formula: C₂₈H₃₇N₅O₇
• Appearance: white powder
• Solubility: Soluble in water (up to 1 mg/mL)
• Stability: Store refrigerated at –20 °C to maintain stability and prevent degradation
• Properties: Endogenous opioid-like peptide that binds to μ and δ opioid receptors; provides anti-wrinkle, smoothing, regenerative, and skin-conditioning effects; improves skin barrier and elasticity with a Botox-like action.